人主動脈瓣膜間質(zhì)細(xì)胞永生化
具體成交價以合同協(xié)議為準(zhǔn)
- 公司名稱 上海富雨生物科技有限公司
- 品牌
- 型號
- 產(chǎn)地
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時間 2025/4/24 11:29:12
- 訪問次數(shù) 110
聯(lián)系方式：陳壽彬18956075901 查看聯(lián)系方式
聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息，謝謝!
人主動脈瓣膜間質(zhì)細(xì)胞永生化
benefit. Low- and interlkdiate-grade NETs predominantly lack factors associated with response to ICIs treatlknt, like immune cell infiltration, and have an immunosuppressive tumour lktabolism and microenvironlknt. In addition, because of its potential influence on the response to ICIs, major interest has been shown in the
suppressor cells, which are known for their tumor promoting and immunosuppressive functions, constitute the major source of excessive cysteine cathepsin activity in cancer. Since they are enriched in the tumor microenvironment, cysteine cathepsins represent exciting targets for
| 種屬 | 人 |
| 組織來源 | 正常主動脈組織 |
| 傳代比例 | 1:2傳代 |
| 培養(yǎng)基配置 | 基礎(chǔ)培養(yǎng)基500ml ；生長添加劑5ml ；胎牛血清50ml ；雙抗5ml |
| 簡介 | 主動脈瓣施半月瓣 ，位于左心室和主動脈之間 ，抑制射入主動脈的血液回流入左心室 ，主動脈瓣鈣化可引起主動脈瓣 狹窄關(guān)閉不全等 ，施導(dǎo)致老年退行性心瓣膜病的重要病理改變 ，其發(fā)病率隨著年齡的增加而升高。有研究表明 ，瓣膜 間質(zhì)細(xì)胞向城固細(xì)胞樣細(xì)胞表型轉(zhuǎn)化有可能是主動脈瓣膜鈣化的病理改變基礎(chǔ)之一。 |
| 形態(tài) | 長梭形細(xì)胞樣、不規(guī)則細(xì)胞樣 |
| 生長特征 | 貼壁生長 |
| 細(xì)胞檢測 | 平滑肌肌動蛋白(α -SMA）免疫熒光染色法熒光鑒定 ，細(xì)胞純度可達(dá)90%以上 ，不含有HIV-1、HBV、HCV、支原 體、細(xì)菌、酵母和真菌等。 |
| 倍增時間 | 每周 2 至 3 次 |
| 換液頻率 | 2-3天換液一次 |
| 備注 | 人主動脈瓣膜間質(zhì)細(xì)胞永生化該細(xì)胞通過慢病毒轉(zhuǎn)染的方式攜帶SV40基因。 |
benefit. Low- and interlkdiate-grade NETs predominantly lack factors associated with response to ICIs treatlknt, like immune cell infiltration, and have an immunosuppressive tumour lktabolism and microenvironlknt. In addition, because of its potential influence on the response to ICIs, major interest has been shown in the
suppressor cells, which are known for their tumor promoting and immunosuppressive functions, constitute the major source of excessive cysteine cathepsin activity in cancer. Since they are enriched in the tumor microenvironment, cysteine cathepsins represent exciting targets for
采購中心
化工儀器網(wǎng)