產(chǎn)品名稱:Rabbit Anti-Zyxin antibody
反應: (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
免疫原:KLH conjugated synthetic peptide derived from human Zyxin
保存:-20℃
保質(zhì)期:1年
產(chǎn)品名稱:Anti-Zyxin antibody
Mouse Anti-Zyxin
別名:ESP2; HED2; ZYX; Zyxin2.
免疫原:KLH conjugated synthetic peptide derived from human Zyxin
保存:-20℃
保質(zhì)期:1年
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
應用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
保存:-20℃
保質(zhì)期:1年
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
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