anti-Mouse IgG/Cy3抗體  瑞齊生物抗體應(yīng)用于WB、IHC、IF、ELISA等實驗中“

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【產(chǎn)品規(guī)格】：0.1ml/0.2ml
【產(chǎn)品價格】：詢價（電詢或客服）
【抗體來源】：Rabbit OR Mouse or Goat
【產(chǎn)品用途】：科研實驗，用于ELISA實驗、免疫組化實驗，WB實驗，IF實驗等，可，索取產(chǎn)品說明書！
【性    狀】： Lyophilized or Liquid
【濃    度】： 1mg/1ml
【亞    型】： IgG
【貯    存】： 貯存于-20℃.
【相關(guān)標(biāo)記】：HRP  Biotin  Gold  RBITC  AP  FITC  Cy3  Cy5  Cy5.5  Cy7 PE  PE-Cy3  PE-CY5  PE-CY5.5  PE-CY7  APC  Alexa Fluor 350   Alexa Fluor 488    Alexa Fluor 555     Alexa Fluor 647
【產(chǎn)品別名】：

  ，多肽抗原，蛋白抗體Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.

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