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化工儀器網(wǎng)>產(chǎn)品展廳>試劑標(biāo)物>行業(yè)專用試劑>生化與分子生物學(xué)用試劑>0216011080 DSS硫酸葡聚糖100g

0216011080 DSS硫酸葡聚糖100g

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  • 公司名稱 廣州威佳科技有限公司
  • 品牌 MP Biomedicals
  • 型號 0216011080
  • 產(chǎn)地 美國
  • 廠商性質(zhì) 經(jīng)銷商
  • 更新時間 2018/3/27 15:10:59
  • 訪問次數(shù) 324
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DSS硫酸葡聚糖DSS硫酸葡聚糖

聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息,謝謝!


生命科研實驗用品專業(yè)供應(yīng)商3000種以上現(xiàn)貨經(jīng)銷進(jìn)口試劑,消耗品,儀器及提供技術(shù)服務(wù)。

廣州威佳科技有限公司成立于2000年,是一家涉足于生命科學(xué)和生物技術(shù)領(lǐng)域的民營企業(yè),致力于向國內(nèi)生命科學(xué)研究人員提供*的產(chǎn)品和服務(wù)。經(jīng)過10年來的不懈努力,本公司建立了涵蓋分子生物學(xué)、細(xì)胞生物學(xué)、免疫學(xué)、信號傳導(dǎo)和神經(jīng)科學(xué)等領(lǐng)域的產(chǎn)品供應(yīng)線,在各個領(lǐng)域內(nèi)向用戶提供*水平和質(zhì)量穩(wěn)定的產(chǎn)品,在這10年里公司茁壯成長,不斷完善產(chǎn)品,公司規(guī)模不斷擴大,銷售額年年攀高。

代理經(jīng)銷國內(nèi)外多家,主要有: Amresco ,epitomics, Sigma, bioind ,MPBIO ,Mlilipore ,NEB,SAB,MBL,Roche,abnova,Novus,Oxygen,Lifespan,MD,CorningFermentas(MBI),Rainin ,Abcam,GE,Merck,CST,Labvision,Gibco,Hyclone,Pierce,SantaCruz,BD, R&D ,Peprotech,OXIOD,VECTOR,ebioscience,Alpha,博士德,普利萊,四季青,碧云天,普欣,金麥克,吉諾等我們還建立了標(biāo)準(zhǔn)化的實驗室,*的為國內(nèi)廣大科研工作者解決Z實際的問題,做*質(zhì)、Z便捷、Z實效的服務(wù)。

技術(shù)服務(wù)涉及:細(xì)胞培養(yǎng),ELISA, WB, 免疫組化, 熒光定量PCR等。

我們秉承“全面,專業(yè),優(yōu)質(zhì),快捷”的服務(wù)理念,協(xié)助推動中國生命科學(xué)研究的進(jìn)步。為了更好更快捷的提供服務(wù),公司存?zhèn)淞舜罅楷F(xiàn)貨,配合優(yōu)秀的銷售隊伍以及專業(yè)的技術(shù)支持,隨時為客戶提供*質(zhì)的服務(wù),客戶的滿意和信任是我們較大的動力。

試劑、實驗室耗材、儀器

DSS-zui有效的腸炎造模試劑
 

DSS硫酸葡聚糖 是葡聚糖的聚陰離子衍生物。我們的DSS因為其具有zui高質(zhì)量,純度和可重復(fù)性,使其應(yīng)用于很多領(lǐng)域,包括:臨床,分子生物學(xué),生物醫(yī)學(xué)甚至化妝品領(lǐng)域.
 

DSS硫酸葡聚糖 具有如下特性:
水溶性聚陰離子復(fù)合物
形成無色澄清溶液,似天然粘多糖
高純度及良好的穩(wěn)定性
可被自然生態(tài)系統(tǒng)降解
可作為敏感性天然成分的穩(wěn)定劑

炎性腸?。↖BD)的特征是慢性、復(fù)發(fā)性胃腸道炎癥,其可增加患結(jié)腸炎相關(guān)性癌癥的風(fēng)險。已經(jīng)有幾種動物模型被用于研究腸炎,其中一個模型就是通過小鼠口服葡聚糖硫酸鈉(DSS)的水溶液來誘導(dǎo)慢性腸炎。DSS誘導(dǎo)的腸炎模型是自發(fā)的,并且可以用來評估IBD的治療潛力.

使用zui有效的DSS硫酸葡聚糖 可以加速您的IBD研究。我們的DSS具有以下優(yōu)勢:

  • zui高的硫含量 : 19%
  • zui高的手性:+104°比旋光度
  • zui低的pH值:6.2(1%水溶液)

的結(jié)果!

Bamba等人(2012)對3種不同的DSS進(jìn)行了比較分析,研究了它們的化學(xué)性質(zhì)和細(xì)胞毒性以及引發(fā)的腸炎嚴(yán)重性。他們的研究結(jié)論是,我們的DSS可引發(fā)一種嚴(yán)重的腸炎,通過體重變化,DAI評分,結(jié)腸重量/長度和組織學(xué)評分這些指標(biāo)顯示.

DSS硫酸葡聚糖 訂購4007-169-114

1) Mouli, V.P., Ananthakrishnan, A.N. Review article: Vitamin D and inflammatory bowel diseases (2014) Alimentary Pharmacology and Therapeutics, 39 (2), pp. 125-136.

2) Salcedo, R., Cataisson, C., Hasan, U., Yuspa, S.H., Trinchieri, G. MyD88 and its divergent toll in carcinogenesis (2013) Trends in Immunology, 34 (8), pp. 379-389.

3) Zindl, C.L., Lai, J.-F., Lee, Y.K., Maynard, C.L., Harbour, S.N., Ouyang, W., Chaplin, D.D., Weaver, C.T. IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis (2013) Proceedings of the National Academy of Sciences of the United States of America, 110 (31), pp. 12768-12773.

4) Tanaka, T., Ishikawa, H. Mast cells and inflammation-associated colorectal carcinogenesis (2013) Seminars in Immunopathology, 35 (2), pp. 245-254.

5) Tanaka, T. Development of an inflammation-associated colorectal cancer model and its application for research on carcinogenesis and chemoprevention (2012) International Journal of Inflammation, 2012, art. no. 658786.

5) Sussman, D.A., Santaolalla, R., Strobel, S., Dheer, R., Abreu, M.T. Cancer in inflammatory bowel disease: Lessons from animal models (2012) Current Opinion in Gastroenterology, 28 (4), pp. 327-333.

6) Perše, M., Cerar, A. Dextran sodium sulphate colitis mouse model: Traps and tricks (2012) Journal of Biomedicine and Biotechnology, 2012, art. no. 718617.

7) Vora, P., McGovern, D.P.B. LRRK2 as a negative regulator of NFAT: Implications for the pathogenesis of inflammatory bowel disease (2012) Expert Review of Clinical Immunology, 8 (3), pp. 227-229.

8) Zhao, W.-C., Song, L.-J., Deng, H.-Z. Protective effect of total alkaloids of sophora alopecuroides on dextran sulfate sodium-induced chronic colitis (2011) Chinese Journal of Integrative Medicine, 17 (8), pp. 616-624.

9) Azuma, Y.-T., Nakajima, H., Takeuchi, T. IL-19 as a potential therapeutic in autoimmune and inflammatory diseases (2011) Current Pharmaceutical Design, 17 (34), pp. 3776-3780.

10) Naito, Y., Takagi, T., Uchiyama, K., Yoshikawa, T. Heme oxygenase-1: A novel therapeutic target for gastrointestinal diseases (2011) Journal of Clinical Biochemistry and Nutrition, 48 (2), pp. 126-133.

11) Egea, L., Hirata, Y., Kagnoff, M.F. GM-CSF: A role in immune and inflammatory reactions in the intestine (2010) Expert Review of Gastroenterology and Hepatology, 4 (6), pp. 723-731.

12) Takagi, T., Naito, Y., Uchiyama, K., Yoshikawa, T. The role of heme oxygenase and carbon monoxide in inflammatory bowel disease (2010) Redox Report, 15 (5), pp. 193-201.

13) Shukla, P., Gupta, G., Singodia, D., Shukla, R., Verma, A.K., Dwivedi, P., Kansal, S., Mishra, P.R. Emerging trend in nano-engineered polyelectrolyte-based surrogate carriers for delivery of bioactives (2010) Expert Opinion on Drug Delivery, 7 (9), pp. 993-1011.

14) Solomon, L., Mansor, S., Mallon, P., Donnelly, E., Hoper, M., Loughrey, M., Kirk, S., Gardiner, K. The dextran sulphate sodium (DSS) model of colitis: An overview (2010) Comparative Clinical Pathology, 19 (3), pp. 235-239.

15) Strauch, U.G., Grunwald, N., Obermeier, F., Gürster, S., Rath, H.C. Loss of CD103+ intestinal dendritic cells during colonic inflammation (2010) World Journal of Gastroenterology, 16 (1), pp. 21-29.

16) Maxwell, J.R., Brown, W.A., Smith, C.L., Byrne, F.R., Viney, J.L. Methods of inducing inflammatory bowel disease in mice (2009) Current Protocols in Pharmacology, (SUPPL.47), pp. 5.58.1-5.58.37.

17) Waldner, M.J., Neurath, M.F. Chemically induced mouse models of colitis (2009) Current Protocols in Pharmacology, (SUPPL. 46), pp. 5.55.1-5.55.15.

18) Nishihira, J., Mitsuyama, K. Overview of the role of macrophage migration inhibitory factor (MIF) in inflammatory bowel disease (2009) Current Pharmaceutical Design, 15 (18), pp. 2104-2109.

19) Soeda, S., Sakata, A., Ochiai, T., Yasuda, K., Kuramoto, Y., Shimeno, H., Toda, A., Eyanagi, R., Hikishima, S., Yokomastu, T., Shibuya, S. Sphingomyelinase inhibition suggests a possible new strategy for the treatment of inflammatory bowel disease (2008) Current Drug Therapy, 3 (3), pp. 218-225.

20) Kawada, M., Arihiro, A., Mizoguchi, E. Insights from advances in research of chemically induced experimental models of human inflammatory bowel disease (2007) World Journal of Gastroenterology, 13 (42), pp. 5581-5593.

21) Clapper, M.L., Cooper, H.S., Chang, W.-C.L. Dextran sulfate sodium-induced colitis-associated neoplasia: A promising model for the development of chemopreventive interventions (2007) Acta Pharmacologica Sinica, 28 (9), pp. 1450-1459.

22) Butterworth, J.R. Another important function for an old friend! The role of iron in colorectal carcinogenesis (2006) Gut, 55 (10), pp. 1384-1386.

23) Di Pace, R.F., Massa, S., Ribeiro, O.G., Cabrera, W.H.K., De Franco, M., Starobinas, N., Seman, M., Ibañez, O.C.M. Inverse genetic predisposition to colon versus lung carcinogenesis in mouse lines selected based on acute inflammatory responsiveness (2006) Carcinogenesis, 27 (8), pp. 1517-1525.

24) Guarner, F. Inulin and oligofructose: Impact on intestinal diseases and disorders (2005) British Journal of Nutrition, 93 (SUPP), pp. S61-S65.

25) Dagenais, S., Haldeman, S., Wooley, J.R. Intraligamentous injection of sclerosing solutions (prolotherapy) for spinal pain: A critical review of the literature (2005) Spine Journal, 5 (3), pp. 310-328. Cited 30 times.

26) Mirvish, S.S., Haorah, J., Zhou, L., Hartman, M., Morris, C.R., Clapper, M.L. N-Nitroso compounds in the gastrointestinal tract of rats and in the feces of mice with induced colitis or fed hot dogs or beef (2003) Carcinogenesis, 24 (3), pp. 595-603.

DSS硫酸葡聚糖 溫馨提示:不可用于臨床治療。

 



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