模塊化微流控芯片用微濾器

微工程過(guò)濾器可用于高精度微?；蚣?xì)胞分離與傳統(tǒng)濾波器不同的是，這些濾波器是由高精度批量生產(chǎn)技術(shù)生產(chǎn)的規(guī)則和高精度孔陣列構(gòu)成的。

這些孔的形狀、大小和密度都是專門(mén)用來(lái)分離外周血中循環(huán)腫瘤細(xì)胞、胎兒細(xì)胞或內(nèi)皮祖細(xì)胞的。它們還可用于分離微生物或用于復(fù)雜溶液過(guò)濾的其他目的。

通常，過(guò)濾器的工作區(qū)域直徑為9mm，包含多達(dá)數(shù)百萬(wàn)個(gè)規(guī)則孔過(guò)濾器的厚度可以變化到十分之幾微米過(guò)濾器的機(jī)械穩(wěn)定性由附加的支承環(huán)保證，過(guò)濾器的總尺寸為直徑13mm。

微孔可以有不同的形狀：

漏斗形狀

圓柱

圓錐形的

孔的小直徑可以是：

6微米

5微米

1μm（僅適用于漏斗形狀）

音高可以是：

10微米

30微米

模塊化微流控芯片用微濾器

Micro-engineered filters are available for high precision microparticle or cell isolation. Unlike conventional filters, these filters are made of regular and high precision hole arrays produced by high precision techniques of mass production.

The shape, size and density of the holes are designed to specifically allow the isolation of circulating tumor cells, fetal cells or endothelial progenitors in peripheral bloods. They can also be used for the isolation of microorganisms or other purposes of complex solution filtration.

Typically, the working area of the filter is 9 mm in diameter, containing up to several millions of regular holes. The thickness of the filter can vary up to a few tenths of micrometers. The mechanic stability of the filter is ensured by an additional supporting ring and the total filter size is of 13 mm in diameter.

The microholes can have different shape:

• Funnel shape
• Cylinder
• Conical

The smallest diameter of the hole can be:

• 6 μm
• 5 μm
• 1 μm (only for funnel shape)

Pitch can be:

• 10 μm 
• 30 μm