流體剪切力系統(tǒng)

美國flexcell str-4000細胞流體剪切應力加載培養(yǎng)系統(tǒng)介紹：

●為細胞提供各種形式的流體切應力：穩(wěn)流式、脈沖式、往返式震蕩式剪切切應力。
●在經(jīng)過特殊基質(zhì)蛋白包被細胞培養(yǎng)載片上培養(yǎng)細胞：
Streamer載片規(guī)格：25mm x 75mm x 1.0mm
Flexflow蓋片規(guī)格：25mm x 75mm x 0.2mm
●計算機控制的蠕動泵可以調(diào)節(jié)切應力的大小，從0-35 dynes/cm2
●Osci-Flow液體控制儀提供往返式或者脈沖式的流體切應力。
●檢測細胞在液流作用下的排列反應。
●設備易拆卸并可高溫消毒。
●streamer多達6通道，每個通道放不同載片，可培養(yǎng)不同的細胞
●FlexFlow提供流體切應力同時抻拉細胞，并可在顯微鏡下進行實時觀察

flexcell str-4000細胞流體剪切應力加載培養(yǎng)系統(tǒng)應用文獻：

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美國Flexcell公司，成立于1987年，該公司專注于細胞力學培養(yǎng)產(chǎn)品的設計和制造。以提供*的體外細胞拉應力、壓應力和流體剪切應力加載刺激系統(tǒng)以及配套的培養(yǎng)板、硅膠膜載片等耗材*。

Flexcell細胞組織力學培養(yǎng)系統(tǒng)不僅能對各種2D、3D細胞組織提供拉應力、壓應力、切應力刺激加載,而且還可以提供拉應力和切應力混合力同時加載;不僅能對細胞組織進行機械力加載刺激,而且還能進行三維培養(yǎng)、人工生物組織構建、動力模擬;不僅能單軸向牽張拉伸,而且還可以雙軸向牽張拉伸;不僅可以根據(jù)實驗需要調(diào)節(jié)受力大小,而且還可以模擬不同受力時間。

Flexcell*的StageFlexer拉應力顯微設備、StagePresser壓應力顯微設備、Flex Flow切應力顯微設備，可在加力培養(yǎng)的同時實時觀察研究細胞組織在力作用下的反應變化；*的flexstop隔離閥能使同一塊培養(yǎng)板里的細胞組織一部分受力，一部分不受力，方便進行對比實驗

這些系統(tǒng)智能、精準誘導來自各種細胞、組織在拉應力、壓應力和流體切應力作用下發(fā)生的生化生理變化，專業(yè)、細膩的闡釋了體外細胞、組織機械力刺激加載、力學信號感受和響應機制。對研究細胞的形態(tài)結構及功能，細胞的生長、發(fā)育、成熟、增殖、衰老、凋亡、死亡及癌變以及通路表達，細胞信號傳導及基因表達的調(diào)控，細胞的分化及其調(diào)控機理具有重要意義。