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化工儀器網(wǎng)>產(chǎn)品展廳>試劑標(biāo)物>行業(yè)專用試劑>生物試劑>A02314 MonoRab™ GS Linker Antibody P...

A02314 MonoRab™ GS Linker Antibody PE, mAb, Rabbit

參考價(jià) 2800
訂貨量 ≥1
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漠寶(廈門)生物科技有限公司(Amobio Biotech Co.,Ltd)是一家致力于生命科學(xué)和生物技術(shù)領(lǐng)域的高科技企業(yè),依托于廈門大學(xué)人才力量。公司主要專注于細(xì)胞生物學(xué)與蛋白質(zhì)分析相關(guān)產(chǎn)品的開發(fā)與銷售。公司主要代理和自產(chǎn)國產(chǎn)優(yōu)質(zhì)試劑和設(shè)備,以期為生命科學(xué)多研究領(lǐng)域的科研人員提供美而精的產(chǎn)品。我們相信經(jīng)過幾年的努力,漠寶生物一定能成為細(xì)胞生物學(xué)、免疫學(xué)等領(lǐng)域優(yōu)質(zhì)的供應(yīng)商,促進(jìn)國產(chǎn)試劑替代進(jìn)口試劑的發(fā)展,加速國產(chǎn)關(guān)鍵性原料研發(fā)進(jìn)程,減輕困擾我們的進(jìn)口試劑和設(shè)備依賴病。


漠寶生物將以更好的客戶服務(wù)、完備的產(chǎn)品供應(yīng)、深厚的專業(yè)知識和優(yōu)秀的人脈資源,在同行業(yè)中保持良好的企業(yè)形象和競爭優(yōu)勢。我們將不斷引進(jìn)和開發(fā)優(yōu)質(zhì)的產(chǎn)品,滿足廣大客戶的需求,在世界各國大力發(fā)展生命科學(xué)的時(shí)代背景下,我們將以為“中國生命科學(xué)發(fā)展而盡上一份綿薄之力"為使命,為科學(xué)人員創(chuàng)造的科研成果提供強(qiáng)有力的支撐。


公司將不斷豐富和借助于優(yōu)秀人才和技術(shù)優(yōu)勢,致力于研發(fā)、生產(chǎn)出品質(zhì)優(yōu)異,行業(yè)前茅的細(xì)胞生物學(xué)與蛋白質(zhì)分析產(chǎn)品,力爭在不久的將來將漠寶打造為生命科學(xué)領(lǐng)域的優(yōu)秀品牌。


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供貨周期 一周 應(yīng)用領(lǐng)域 醫(yī)療衛(wèi)生,食品/農(nóng)產(chǎn)品,化工,生物產(chǎn)業(yè),制藥/生物制藥

產(chǎn)品概述

SpecificityThis product recognizes (GnS)m linker(n≥2, m≥2) in proteins, antibodies or cells, such as (G2S)2 linker, (G2S)4 linker, (G3S)3 linker, (G4S)2 linker and (G4S)3 linker, etc.
Host SpeciesRabbit
ImmunogenA synthetic peptide (GGGGSGGGGSGGGGS) coupled to BSA
ConjugatePhycoerythrin (PE)










應(yīng)用指導(dǎo)

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ApplicationRecommended Usage
Flow Cytometry1:50











產(chǎn)品屬性

FormLiquid
Storage BufferSupplied in PBS (pH 7.2), containing gelatin and 0.03% ProClin300.
Storage InstructionsStored at 4°C and it should be protected from prolonged exposure to light. Do not freeze. This product is stable for 1 year upon receipt, when handled and stored as instructed.
PurificationProtein A affinity column
IsotypeRabbit IgG, κ
ClonalityMonoclonal
Clone ID20H7
NoteGenScript can customize this product per customer's request including product size, buffer components, etc.


















圖例

技術(shù)背景

Target BackgroundA linker is an amino acid chain that connects two fused proteins, allowing for the appropriate separation of protein functional domains or the maintenance of necessary inter-domain interactions. The most commonly used flexible linker is the poly-Glycine-Serine (GS) linker. A very important application of the flexible GS linker is connecting the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs). Due to its flexible structure and appropriate linker sequence length, the (GGGGS)3 linker has been shown to allow for the correct orientation of the VH and VL domains, and it does not interfere with the folding of the protein domains in scFv construction[1,2].
SynonymsGS Linker;Glycine-serine linker; (G?S)? Linker; poly-Glycine-Serine; (GGGGS)?;
Reference[1] Huston,J,S,et al.Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli.[J].Proceedings of the National Academy of Sciences, 1988, 85(16):5879-5883.
[2] Chen X , Zaro J ,Shen, Wei‐Chiang.Fusion Protein Linkers: Effects on Production, Bioactivity, and Pharmacokinetics[M].John Wiley & Sons, Inc. 2013.























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