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化工儀器網(wǎng)>產(chǎn)品展廳>試劑標(biāo)物>生化試劑>蛋白質(zhì)/多肽>UA040011 FLT-3L Protein, Human

UA040011 FLT-3L Protein, Human

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  • 公司名稱 杭州斯達(dá)特生物科技有限公司
  • 品牌 Starter/斯達(dá)特
  • 型號(hào) UA040011
  • 產(chǎn)地 江蘇 南京
  • 廠商性質(zhì) 生產(chǎn)廠家
  • 更新時(shí)間 2025/7/16 11:31:11
  • 訪問(wèn)次數(shù) 48

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杭州斯達(dá)特是一家集研發(fā)、生產(chǎn)、銷售與技術(shù)服務(wù)為一體的高科技生物公司,志在為全球生物醫(yī)學(xué)研究、體外診斷企業(yè)、生物制藥企業(yè)提供優(yōu)質(zhì)的抗體、蛋白、試劑盒和定制服務(wù),包括科研抗體、CDx和IVD抗原和抗體原料、一步法ELISA試劑盒、鼠兔通用二抗試劑盒以及其他用途的免疫試劑整體解決方案。


公司核心團(tuán)隊(duì)深耕抗體研發(fā)十五年,具有成功開(kāi)發(fā)數(shù)千種精準(zhǔn)醫(yī)學(xué)抗體、科研抗體的豐富經(jīng)驗(yàn)。公司建立了多物種單B細(xì)胞抗體開(kāi)發(fā)平臺(tái)(兔單抗,鼠類單抗等)、傳統(tǒng)鼠單抗、重組蛋白表達(dá)平臺(tái)及完善的抗體應(yīng)用驗(yàn)證和檢測(cè)體系(包括免疫層析,酶聯(lián)免疫,流式分析,免疫組化,免疫印跡,免疫熒光,免疫沉淀等)。已正式通過(guò)歐盟98/79/EC認(rèn)證、ISO9001認(rèn)證和ISO13485認(rèn)證。


公司以加速人類、疾病診斷、為人類和動(dòng)物健康保駕護(hù)航為使命,以扎實(shí)的科學(xué)技術(shù)為基礎(chǔ),秉承向正向善向上的價(jià)值觀,以行業(yè)客戶需求為導(dǎo)向,愿與全球同仁精誠(chéng)合作,共啟健康新篇章。


斯達(dá)特,專注于抗體研發(fā)和制造,您的最佳抗體優(yōu)選伙伴。

抗體,蛋白,試劑盒

Fms-like tyrosine kinase 3 (FLT-3) is a cytokine receptor expressed on the surface of bone-marrow progenitor of hematopoietic cells. FLT-3 ligands (FLT-3L) are produced by peripheral blood mononuclear cells, and found in various human body fluids. FLT-3L is a cytokine that promotes the survival, proliferation, and differentiation of hematopoietic progenitors in synergy with other growth factors, such as stem cell factor. FLT-3 signal is involved in the regulation of vessel formation as well as B cell differentiation, suggesting that FLT-3 signal contributes to the pathogenesis of vascular abnormalities and immune dysregulation in rheumatic diseases. The FLT-3L plays a role in complex cytokine interactions in the process of proliferation and differentiation of various hematologic periods while it is a router in early cell interactions. The FLT-3 receptor is a transmembrane protein that reaches its biologically active form by proteolytic lysis. It was suggested that with its proliferative activity, the FLT-3L also has an antitumor effect. The FLT-3L is an earlier releaser of the progenitor cells from the stem cell pool according to GM-CSF and G-CSF actions, which occur later. Additionally, a study on mouse models showed that the FLT-3L increases the blood amount of CD34 cells. These features gave rise to the idea that recombinant FLT-3L could be used in bone marrow transplantation to evoke cell mobilization. Similarly, some authors theorized that the FLT-3L could be used in many pathological diseases such as Fanconi and aplastic anemia that originated from stem cell defects.

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