UA011132 APLP2/Amyloid-like protein 2 His Tag Protein, Human
- 公司名稱 杭州斯達特生物科技有限公司
- 品牌 Starter/斯達特
- 型號 UA011132
- 產(chǎn)地 江蘇 南京
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時間 2025/7/16 20:46:46
- 訪問次數(shù) 40
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YWK-II protein/APLP2 is a member of an evolutionarily conserved APP family that includes amyloid precursor protein (APP) and amyloid precursor-like protein-1 (APLP1). YWK-II/APLP2 functions as a novel G(0)-protein-coupled receptor for Müllerian inhibiting substance (MIS) in cell survival. Human leukocyte antigen-B-associated transcript 3 (Bat3), an important regulator involved in apoptosis, can interact with YWK-II/APLP2 and enhance its stability by reducing its ubiquitylation and degradation by the ubiquitin-proteasome system. May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.