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化工儀器網(wǎng)>產(chǎn)品展廳>實驗室常用設(shè)備>粉碎/研磨設(shè)備>其它粉碎研磨設(shè)備>25 ug Anti-Human CD20 eFluor® 615

25 ug Anti-Human CD20 eFluor® 615

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Anti-Human CD20 eFluor® 615

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上海亞培生物科技有限公司

酶聯(lián)免疫試劑盒,ELISA試劑盒,細(xì)胞,抗體,放免試劑盒,實驗耗材,生物儀器,生化試劑,細(xì)胞因子,快速熱啟動PCR試劑盒,DNA聚合酶,血液PCR試劑盒,抗原

Description: The monoclonal antibody L26 recognizes human CD20, a two transmembrane spanning protein found on precursor and mature B lymphocytes. Expression is lost upon differentiation to plasma cells. The levels of CD20 are critical in evaluating malignant B lymphocytes including Non-Hodgkin’s Lymphoma, and Acute B cell, Chronic Lymphocytic and Hairy-Cell Leukemias. CD20 plays a role in B cell differentiation and activation. The structure of the protein shows a small extracellular loop with the carboxy and amino termini in the cytoplasmic compartment. The L26 antibody recognizes an epitope in the cytoplasmic domain and therefore requires permeabilization of the tissue for staining applications. Unlike many anti-CD20 antibodies that recognize the extracellular domain, the epitope recognized by L26 will not be blocked by therapeutic antibodies to CD20, like Rituximab.



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