產品: millipore 
貨號: DPP4
Description: DPP IV Inhibitor
Qty/Pk: 1 mL
Entrez Gene Summary: The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.
UniProt Summary: FUNCTION: SwissProt: P27487 # Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. Plays a role in T-cell activation.
SIZE: 766 amino acids; 88279 Da
SUBUNIT: Homodimer or heterodimer with Seprase （FAP）.
SUBCELLULAR LOCATION: Dipeptidyl peptidase 4 soluble form: Secreted. & Cell membrane; Single-pass type II membrane protein.
TISSUE SPECIFICITY: Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon.
PTM: The soluble form （SDPP） derives from the membrane form （MDPP） by proteolytic processing.
SIMILARITY: SwissProt: P27487 ## Belongs to the peptidase S9B family. DPPIV subfamily.