When two proteins interact and bind, conformational changes in the proteins, and rearrangement of the solvent in the vicinity of the binding site, result in the absorption or generation of heat. Quantification of this reaction heat by ITC provides a complete thermodynamic description of the binding interaction, the stoichiometry of binding, and the association constant; in addition, if structural information is available, the contributions of specific amino acids mediating the binding event can be identified and their thermodynamic contributions quantified.
提供商 |
TA儀器 | 下載次數(shù) |
63次 |
資料大小 |
1.4MB | 資料類(lèi)型 |
PDF 文件 |
資料圖片 |
-- | 瀏覽次數(shù) |
610次 |
(空格分隔,最多3個(gè),單個(gè)標(biāo)簽最多10個(gè)字符)
會(huì)員.png)
22
立即詢價(jià)
您提交后，專(zhuān)屬客服將第一時(shí)間為您服務(wù)