會(huì)員.png)
QQ交談
您所在位置：請(qǐng)輸入產(chǎn)品關(guān)鍵字：
郵編：200431
聯(lián)系人：王小姐
電話：021-56640936
傳真：021-33250231
手機(jī)：13122441390 15900755943
留言：發(fā)送留言
個(gè)性化：www.shifengsj.com
網(wǎng)址：www.shfeng-edu.com
商鋪：http://www.duoo135.com/st236594/
cdc25和chk1與細(xì)胞凋亡
點(diǎn)擊次數(shù)：1262 發(fā)布時(shí)間：2017-5-24
<img alt="cdc25和chk1與細(xì)胞凋亡" cdc25和chk1與細(xì)胞凋亡"="" border="1" height="384" data-cke-saved-src="http://www.bio1000。。ｃｏｍ/uploads/allimg/120409/1201226-0.gif" src="http://www.bio1000。。ｃｏｍ/uploads/allimg/120409/1201226-0.gif" width="576" style="vertical-align: middle; border: 0px;">
cdc25和chk1在DNA破壞中的作用
Cdc25 is a protein phosphatase responsible for dephosphorylating and activating cdc2, a crucial step in regulating the entry of all eukaryotic Cells into the M-phase of the cell cycle. Cdc25 is phosphorylated throughout interphase but not in mitosis. The primary site for phosphorylation of cdc25 is at Ser216. Phosphorylated cdc25 binds to members of the 14-3-3 family of proteins which prevents its activation of cdc2. Chk1, a protein kinase involved in the DNA damage checkpoint response in fission yeast, has been shown to phosphorylate cdc25 at Ser216 in vitro.