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[供應(yīng)]MGro-case-MesenGro® case 12x500mL 人間充質(zhì)干細(xì)胞培養(yǎng)基
產(chǎn)地:美國(guó)StemRD公司
更新時(shí)間:2025-01-13 09:21:17
有效期:2025年1月13日 -- 2025年7月16日
已獲點(diǎn)擊:337
MesenGro® kit 500mlMGro-500500ml
MesenGro® case of 12 kitsMGro-case12x500ml
產(chǎn)品英文名稱(chēng):MesenGro® case Human mesenchymal stem cells medium, 12x500 ml
產(chǎn)品中文名稱(chēng):MesenGro® case 12x500 ml 人間充質(zhì)干細(xì)胞培養(yǎng)基
重慶市華雅干細(xì)胞技術(shù)有限公司在倉(cāng)庫(kù)備有現(xiàn)貨,歡迎新老客戶:
間充質(zhì)干細(xì)胞具有光明的臨床治療前景。然而,常用培養(yǎng)基含有胎牛血清(FBS),增加了病原體、異種抗原、批間不穩(wěn)定性。美國(guó)FDA正考慮禁止使用FBS于細(xì)胞治療。為此,StemRD成功研制了MessenGro®,一種無(wú)血清、無(wú)異種蛋白、化學(xué)成分明確的人間充質(zhì)干細(xì)胞培養(yǎng)基。
MesenGro® 化學(xué)成分明確,設(shè)計(jì)用于人體骨髓、臍帶血和脂肪組織等間充質(zhì)干細(xì)胞的zui大程度擴(kuò)增。MesenGro® 化學(xué)成分明確是由于它的成分既沒(méi)有化學(xué)合成,也沒(méi)有重組體生產(chǎn)。
人間充質(zhì)干細(xì)胞培養(yǎng)基直接來(lái)源于非人體動(dòng)物細(xì)胞,無(wú)異種蛋白質(zhì)。MesenGro® 如果用于一定組織細(xì)胞培養(yǎng)瓶中無(wú)需鋪板蛋白,可以節(jié)約鋪板材料和鋪板時(shí)間。
MesenGro ® case 12x 500 ml 人間充質(zhì)干細(xì)胞培養(yǎng)基 產(chǎn)品特性:
» 無(wú)血清 Serum-Free
» 無(wú)異種蛋白 Xeno-Free
» 化學(xué)成分明確 Chemically-Defined
» 無(wú)需昂貴的鋪板蛋白 No Plate Coating Necessary
» 生長(zhǎng)分化優(yōu)于血清培養(yǎng)基 Perform Better than FBS Medium
MesenGro® case 12x 500 ml 人間充質(zhì)干細(xì)胞培養(yǎng)基 產(chǎn)品組成成分:
Part A: Mesen Gro基礎(chǔ)培養(yǎng)基 規(guī)格:1x450ml 保存溫度:2-8 ℃,避光 保質(zhì)期:6個(gè)月
Part B: Mesen Gro補(bǔ)充培養(yǎng)基 規(guī)格:1x50ml 保存溫度:-80℃,避光 保質(zhì)期:6個(gè)月
MesenGro® Human mesenchymal stem cells medium 產(chǎn)品英文簡(jiǎn)述:
Human mesenchymal stem cells (hMSCs) hold promise for the treatment of a wide variety of diseases. Currently, fetal bovine serum (FBS) is added to the medium to achieve expansion of hMSCs. However, concerns have been raised over animal-born pathogens, immune reactions and lot-to-lot variations caused by the undefined nature of FBS. To address these issues, StemRD has developed MesenGro®, a chemically-defined, serum-free and xeno-free medium for the expansion of hMSCs.
The MesenGro® Chemically Defined MSC Medium (for simplicity, referred to as “MesenGro” in this document) has been designed for the maximum expansion of human mesenchymal stem cells (MSCs) derived from bone marrow, cord blood, or adipose tissue. MesenGro® is chemically defined as its components are either chemically synthesized, recombinantly produced and purified. It can be considered xeno-free as none of its ingredients are directly derived from non-human animals. MesenGro® further offers the convenience of no plate-coating if used with certain tissue culture vessels (see below), saving cost of coating materials and time needed for coating.
重慶市華雅干細(xì)胞技術(shù)有限公司在倉(cāng)庫(kù)備有現(xiàn)貨,歡迎新老客戶:
StemRD DKKFC-1000 DKK-1 Fc fusion,human WNT inhibitor 人源Dkk-1蛋白Fc融合WNT信號(hào)通路抑制劑,1000ug
英文名稱(chēng): Dkk-1 Fc fusion, human
產(chǎn)品應(yīng)用: WNT信號(hào)通路抑制劑
中國(guó)俗稱(chēng): 人源Dkk-1蛋白Fc融合WNT信號(hào)通路抑制劑 中國(guó)簡(jiǎn)稱(chēng): 人源Dkk-1蛋白Fc融合WNT信號(hào)通路抑制劑
注冊(cè)品牌: StemRD 生產(chǎn)廠家: StemRD公司
訂購(gòu)貨號(hào): DKKFC-1000
規(guī)格型號(hào): 1000ug
保存溫度: -80℃
產(chǎn)品種類(lèi): WNT信號(hào)通路抑制劑
到貨時(shí)間: 2~5天
產(chǎn)品編碼: YS0010089
產(chǎn)品英文名稱(chēng):StemRD DKKFC-1000 Dkk-1 Fc fusion, human, 1000ug
產(chǎn)品中文名稱(chēng):StemRD DKKFC-1000 人源Dkk-1蛋白Fc融合WNT信號(hào)通路抑制劑,1000ug
StemRD DKKFC-1000 Dkk-1 Fc fusion, human, 1000ug 產(chǎn)品簡(jiǎn)介
DKK-1是重組人Dickkopf相關(guān)蛋白1的簡(jiǎn)稱(chēng),是DKK蛋白干細(xì)胞生長(zhǎng)分化調(diào)整因子家族(DKK1-4)的一員。DKK蛋白干細(xì)胞生長(zhǎng)分化調(diào)整因子zui初被認(rèn)為是非洲爪蟾蜍的前期成形細(xì)胞。通過(guò)機(jī)理 研究發(fā)現(xiàn)DKK-1通過(guò)與共同受體LRP5/6一起形成抑制復(fù)合物,可以有效抑制Wnt/β-catenin信號(hào)通路。研究人員發(fā)現(xiàn)敲除DKK-1基因小 鼠的腦部無(wú)法形成,從而證實(shí)Wnt/β-catenin信號(hào)通路的抑制在脊椎動(dòng)物的后模式與前模式發(fā)展中*。
當(dāng)DKK-1融于人IgG1蛋白的Fc片段時(shí),這種融合避免了蛋白在體內(nèi)體外環(huán)境下的顯著失活,有效保證了其穩(wěn)定性。
StemRD DKKFC-1000 人源Dkk-1蛋白Fc融合WNT信號(hào)通路抑制劑,1000ug 產(chǎn)品特性
»StemRD DKKFC-1000人源Dkk-1蛋白干細(xì)胞生長(zhǎng)分化調(diào)整因子Fc融合WNT信號(hào)通路抑制劑,1000ug鑒定純度大于90%
»StemRD DKKFC-1000人源Dkk-1蛋白干細(xì)胞生長(zhǎng)分化調(diào)整因子Fc融合WNT信號(hào)通路抑制劑,1000ug生物活性在培養(yǎng)人細(xì)胞中用TCF受體基因檢測(cè)確定,拮抗劑WNT-3a 100 ng/mL時(shí)其IC50在200 - 1000 ng/ml之間
StemRD DKKFC-1000 Dkk-1 Fc fusion, human, 1000ug 保存方法
The lyophilized protein is stable for at least one year if stored at -80 degreeC. Reconstituted protein is stable for at least four weeks at 4 degree C, but should be stored in aliquots at -80 degree C for longer term. Avoid repeated freeze and thaw.
StemRD DKKFC-1000 Dkk-1 Fc fusion, human, 1000ug 產(chǎn)品英文描述
DKK-1, Dickkopf-related protein-1, is a member of the DKK protein family which includes DKK-1 through DDK-4. DKK was originally identified as a head-forming molecule in Xenopus. Mechanistic studies showed that DKK-1 inhibits the Wnt /β-catenin signaling pathway by forming inhibitory complexes with co-receptor LRP5/6. Inhibition of Wnt/β-catenin signaling is essential for posterior patterning and anterior development in vertebrates, supported by the discovery that DKK-1 knockout mice lack head formation. When DKK-1 is fused to the Fc fragment of human IgG1. This fusion renders stability of the protein in vitro and in vivo without significant loss of activity.
StemRD expresses StemRD DKKFC-1000 Dkk-1 Fc fusion, human, 1000ug in human 293 cells and purifies it by protein A column.
• StemRD DKKFC-050 Dkk-1 Fc fusion, human, 250ug Purity Greater than 90% as determined by SDS-PAGE analysis
• StemRD DKKFC-050 Dkk-1 Fc fusion, human, 250ug Biological Activity The activity was determined by using a TCF reporter gene assay in cultured human cells. The IC50 ranges from 200 - 1000 ng/ml in the inhibition of 100 ng/mL WNT-3a activity. Activity in other assays should be determined by each individual setting.
StemRD人源Dkk-1蛋白Fc融合WNT信號(hào)通路抑制劑系列產(chǎn)品訂購(gòu)信息
StemRD DKK-025 25ug 優(yōu)惠價(jià)格請(qǐng)
StemRD DKK-100 100ug 優(yōu)惠價(jià)格請(qǐng)
StemRD DKK-500 500ug 優(yōu)惠價(jià)格請(qǐng)
StemRD DKKFC-050 50ug 優(yōu)惠價(jià)格請(qǐng)
StemRD DKKFC-250 250ug 優(yōu)惠價(jià)格請(qǐng)
StemRD DKKFC-1000 1000ug 優(yōu)惠價(jià)格請(qǐng)
For research use only. Not intended for human or animal diagnostic or therapeutic uses.
重慶市華雅干細(xì)胞技術(shù)有限公司在倉(cāng)庫(kù)備有現(xiàn)貨,歡迎新老客戶:
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