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CBP10337 | |
| Format | Genomic DNA |
| Description | EGFR S768I lies within the protein kinase domain of the Egfr protein (UniProt.org). S768I results in constitutive phosphorylation of Egfr, increased downstream signaling, and is transforming in cell culture (PMID: 19147750, PMID: 29533785). |
| Technical Data | |
| DNA Change | c.2303G>T |
| AA Change | p.S768I |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000275493 |
| Cosmic ID | COSM6241 |
| Chr position(GRCh37) | chr7:55249005 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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