hCLEC12A/C1498
| I. Background | |
| CLEC12A 屬于 C-型凝集素/C-型凝集素樣結(jié)構(gòu)域（CTL/CTLD）超家族的一員。這個 家族的成員共享一個共同的蛋白質(zhì)折疊，并具有多種功能，如細胞粘附、細胞間信號傳導(dǎo)、 糖蛋白代謝和參與炎癥和免疫應(yīng)答。CLEC12A 基因編碼的蛋白質(zhì)是粒細胞和單核細胞功能 的負調(diào)控因子，參與免疫系統(tǒng)的平衡調(diào)節(jié)。CLEC12A 在自身免疫性疾病如風(fēng)濕性關(guān)節(jié)炎和 多發(fā)性硬化癥的發(fā)展中發(fā)揮著重要作用。 | |
| II. Introduction | |
| Host Cell: | C1498 |
| Expressed gene: | hCLEC12A |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2μg/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| III. Description of Host Cell Line | |
| Organism: | Mus musculus, mouse |
| Tissue: | N/A |
| Morphology: | lymphoblast |
| Growth Properties: | Suspension |
| IV. Representative Data
Figure 1. Recombinant hCLEC12A/C1498 stably expressing hCLEC12A. | |
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